Jun Yu Selected Research

Catenins

1/2023	Targeting YAP1/TAZ in nonsmall-cell lung carcinoma: From molecular mechanisms to precision medicine.
1/2023	Protocadherin 20 maintains intestinal barrier function to protect against Crohn's disease by targeting ATF6.
10/2022	Tartrate-resistant acid phosphatase 5 promotes pulmonary fibrosis by modulating β-catenin signaling.
1/2022	Extracellular Vesicle-Encapsulated MicroRNA-375 from Bone Marrow-Derived Mesenchymal Stem Cells Inhibits Hepatocellular Carcinoma Progression through Regulating HOXB3-Mediated Wnt/β-Catenin Pathway.
1/2022	Unique molecular characteristics of NAFLD-associated liver cancer accentuate β-catenin/TNFRSF19-mediated immune evasion.
12/2021	A novel amplification gene PCI domain containing 2 (PCID2) promotes colorectal cancer through directly degrading a tumor suppressor promyelocytic leukemia (PML).
12/2020	In Colorectal Cancer Cells With Mutant KRAS, SLC25A22-Mediated Glutaminolysis Reduces DNA Demethylation to Increase WNT Signaling, Stemness, and Drug Resistance.
1/2019	TTPAL Promotes Colorectal Tumorigenesis by Stabilizing TRIP6 to Activate Wnt/β-Catenin Signaling.
1/2019	VSTM2A suppresses colorectal cancer and antagonizes Wnt signaling receptor LRP6.
1/2018	CREPT facilitates colorectal cancer growth through inducing Wnt/β-catenin pathway by enhancing p300-mediated β-catenin acetylation.

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Jun Yu Research Topics

Disease

359	Neoplasms (Cancer) 05/2024 - 01/2002
91	Carcinogenesis 01/2024 - 05/2002
89	Stomach Neoplasms (Stomach Cancer) 04/2024 - 01/2002
71	Colorectal Neoplasms (Colorectal Cancer) 05/2024 - 06/2003
68	Inflammation (Inflammations) 04/2024 - 07/2002
62	Hepatocellular Carcinoma (Hepatoma) 05/2024 - 08/2004
58	Neoplasm Metastasis (Metastasis) 01/2024 - 05/2003
46	Infections 01/2024 - 02/2001
44	Pancreatic Neoplasms (Pancreatic Cancer) 05/2024 - 03/2007
42	Adenocarcinoma 01/2024 - 04/2010
37	Fibrosis (Cirrhosis) 04/2024 - 05/2008
32	Fatty Liver 05/2024 - 04/2006
23	Non-alcoholic Fatty Liver Disease 01/2024 - 03/2010
21	Ischemia 01/2020 - 01/2005
20	Liver Cirrhosis (Hepatic Cirrhosis) 02/2024 - 08/2007
19	Colonic Neoplasms (Colon Cancer) 01/2024 - 11/2009
19	Carcinoma (Carcinomatosis) 01/2023 - 08/2002
17	Atherosclerosis 02/2024 - 12/2007
16	Reperfusion Injury 01/2022 - 12/2005
15	Necrosis 01/2024 - 07/2007
15	Hypoxia (Hypoxemia) 01/2021 - 02/2002
15	Lung Neoplasms (Lung Cancer) 03/2020 - 07/2009
14	Alcoholic Fatty Liver 11/2023 - 08/2008
13	Insulin Resistance 03/2024 - 04/2008
13	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 05/2007
12	Liver Neoplasms (Liver Cancer) 03/2024 - 01/2006
11	Dysbiosis 10/2023 - 01/2018
10	Pulmonary Fibrosis (Fibrosing Alveolitis) 11/2023 - 01/2020
9	Mitochondrial Diseases (Mitochondrial Disease) 05/2024 - 01/2016
9	Cysts 01/2022 - 10/2007
9	Obesity 01/2022 - 05/2009
9	Adenoma (Adenomas) 04/2021 - 12/2008
8	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 12/2023 - 09/2010
8	Neoplasms, Cystic, Mucinous, and Serous 10/2023 - 04/2009
8	Leukemia 04/2023 - 02/2009
8	COVID-19 12/2022 - 01/2021
8	Myocardial Ischemia (Ischemic Heart Diseases) 01/2022 - 04/2013
8	Cerebral Hemorrhage 02/2021 - 09/2004
8	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2017 - 07/2009

Drug/Important Bio-Agent (IBA)

109	Proteins (Proteins, Gene)FDA Link 01/2024 - 01/2002
78	Biomarkers (Surrogate Marker)IBA 01/2024 - 04/2007
55	MicroRNAs (MicroRNA)IBA 01/2022 - 09/2008
54	Messenger RNA (mRNA)IBA 01/2024 - 01/2002
45	CytokinesIBA 04/2024 - 07/2007
37	DNA (Deoxyribonucleic Acid)IBA 04/2024 - 06/2003
35	RNA (Ribonucleic Acid)IBA 04/2024 - 03/2011
22	Small Interfering RNA (siRNA)IBA 01/2024 - 07/2007
22	CateninsIBA 01/2023 - 01/2011
21	Transcription Factors (Transcription Factor)IBA 01/2024 - 06/2003
19	Choline (Choline Chloride)IBA 01/2024 - 04/2007
17	CholesterolIBA 05/2024 - 02/2009
17	Anti-Bacterial Agents (Antibiotics)IBA 10/2023 - 09/2003
16	LipidsIBA 01/2024 - 02/2008
16	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020 - 01/2005
15	Methionine (L-Methionine)FDA Link 11/2022 - 04/2007
14	Long Noncoding RNAIBA 11/2023 - 11/2016
13	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2024 - 04/2006
13	Therapeutic UsesIBA 01/2022 - 09/2010
12	Indicators and Reagents (Reagents)IBA 05/2024 - 09/2010
12	EnzymesIBA 02/2024 - 07/2012
12	LigandsIBA 08/2023 - 06/2005
12	Glucose (Dextrose)FDA LinkGeneric 08/2023 - 01/2006
12	InterleukinsIBA 01/2023 - 07/2007
11	6-methyladenineIBA 01/2024 - 01/2021
11	InterferonsIBA 11/2023 - 04/2012
10	ChromatinIBA 04/2024 - 01/2012
10	LipopolysaccharidesIBA 03/2024 - 04/2011
10	CarcinogensIBA 01/2024 - 01/2005
10	N-methyladenosineIBA 01/2024 - 01/2021
10	Bleomycin (Blenoxane)FDA LinkGeneric 01/2024 - 04/2011
10	AzoxymethaneIBA 12/2023 - 12/2012
10	Amino Acids FDA Link 03/2023 - 01/2005
10	ChemokinesIBA 10/2022 - 05/2007
10	Phosphotransferases (Kinase)IBA 01/2021 - 03/2007
10	Interleukin-6 (Interleukin 6)IBA 04/2018 - 04/2006
10	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 09/2010 - 05/2003
9	NF-kappa B (NF-kB)IBA 02/2024 - 11/2005
9	Immune Checkpoint InhibitorsIBA 12/2023 - 01/2020
9	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2021 - 01/2016
9	Peptides (Polypeptides)IBA 01/2020 - 07/2003
9	PPAR gammaIBA 01/2019 - 01/2006
9	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2018 - 07/2002
8	InflammasomesIBA 02/2024 - 01/2016
8	AntioxidantsIBA 02/2024 - 01/2009
8	Fluorouracil (Carac)FDA LinkGeneric 01/2024 - 04/2016
8	Gemcitabine FDA Link 11/2023 - 07/2008
8	CollagenIBA 11/2023 - 01/2009
8	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2023 - 02/2006
7	Apolipoproteins E (ApoE)IBA 01/2023 - 12/2007

Therapy/Procedure

112	Therapeutics 05/2024 - 07/2003
33	Drug Therapy (Chemotherapy) 01/2024 - 09/2008
23	Liver Transplantation 04/2024 - 06/2004
16	Immunotherapy 04/2024 - 09/2017
16	Neoadjuvant Therapy 02/2024 - 01/2019
12	Pancreatectomy 08/2023 - 06/2010
11	Adjuvant Chemotherapy 04/2024 - 10/2010
11	Ligation 02/2024 - 01/2009
9	Transplantation 01/2024 - 08/2010
8	Radiotherapy 12/2023 - 09/2010
8	Precision Medicine 11/2023 - 01/2018